MO603PREVALENCE AND PROGNOSTIC SIGNIFICANCE OF MALNUTRITION IN DIALYSIS PATIENTS UNDERGOING ENDOVASCULAR THERAPY FOR PERIPHERAL ARTERY DISEASE

Abstract Background and Aims Malnutrition often coexists with inflammation atherosclerosis is associated adverse clinical outcomes in dialysis patients. However, both prevalence prognostic significance of preexisting malnutrition patients peripheral artery disease (PAD) referred for endovascular therapy are not well known. Method A prospective cohort 395 undergoing PAD between 2005 2019 was studied. Nutritional status assessed at admission by using the Controlling Status (CONUT) score, a simple tool incorporating serum albumin concentration, total lymphocyte count, cholesterol concentration. Patients were divided into 4 groups based on CONUT score: normal nutrition (0–1), mild (2–4), moderate (5–8), severe (9–12). We examined associations all-cause mortality as major limb events (MALE) cardiovascular (MACE) Cox proportional hazards models. Results According to 40.8% moderately or severely malnourished. During median follow-up 2.1 years, 218 (55.2%) died, 211 (53.4%) had MALE, MACE occurred 135 (34.2%) Severely malnourished patients, compared nutritional status, significantly increased risk death (adjusted hazard ratio [HR], 4.83; 95% confidence interval [CI], 2.56 9.12) particular non-cardiovascular HR, 7.20; CI, 3.22 16.08) MALE 2.42; 1.23 4.74) but 1.81; 0.74 4.40). Similar results found when score analyzed continuous variable. Conclusion common strongly among requiring therapy. Clinical trials needed evaluate whether interventions improve PAD.